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Feminization biology There are also sex-specific side effects of AAS. Development of breast tissue in males, a condition called gynecomastia which is usually caused by high levels of circulating estradiol , may arise because of increased conversion of testosterone to estradiol by the enzyme aromatase. This side-effect is temporary; the size of the testicles usually returns to normal within a few weeks of discontinuing AAS use as normal production of sperm resumes. Virilization Female-specific side effects include increases in body hair , permanent deepening of the voice, enlarged clitoris , and temporary decreases in menstrual cycles. Alteration of fertility and ovarian cysts can also occur in females.
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While no single test can detect all breast cancers early, Breastcancer. Over the years, there has been some debate over just how valuable breast self-examination is in detecting breast cancer early and increasing the likelihood of survival. For example, a study of nearly , women in Russia and China reported that breast self-examination does not have a meaningful impact on breast cancer survival rates and may even cause harm by prompting unnecessary biopsies removal and examination of suspicious tissue. Because of the ongoing uncertainty raised by this and other studies, the American Cancer Society no longer recommends breast self-exam as a screening tool for women with an average risk of breast cancer. Each of these screening tools works in a different way and has strengths and weaknesses.
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Context and history[ edit ] Pope Julius II by Raphael Pope Julius II was a "warrior pope" who in his papacy undertook an aggressive campaign for political control, to unite and empower Italy under the leadership of the Church. He invested in symbolism to display his temporal power, such as his procession, in the Classical manner, through a triumphal arch in a chariot after one of his many military victories. It was Julius who began the rebuilding of St.
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